THAT IS?
Plasma rich in growth factors (PRGF) is obtained from the extraction and centrifugation of blood from the same patient. Later, adding calcium chloride activates the secretion of growth factors by the α granules (contained inside the platelets).
Treatment with growth factors has been shown to stimulate local tissue repair mainly through the following mechanisms:
It stimulates the secretion and proliferation of mesenchymal cells (Fibroblasts, tenoviocytes, osteoblasts, chondrocytes and pluripotential stem cells)
- Promotes vascular permeability
- It stimulates the secretion of collagen in the tenoviocyte
- Reduction of IL-1β (pro-inflammatory interleukin)
